HomeTest MenuWound Care
Wound, DFU & SSI Workup · 12-Target Panel

Every Hour Counts in an Infected Wound.

Twelve targets across gram-positive (MRSA included), gram-negative, and Candida wound pathogens — from a single swab.

At a glance
0
Wound Pathogens
0
Candida Species
0%
MRSA Direct Detection
0
Hour TAT for results
The clinical problem
Wound culture under-reports the organisms actually driving the infection.

Diabetic foot ulcers and chronic non-healing wounds are polymicrobial almost by definition. Standard culture preferentially grows the loudest organisms and misses the fastidious species and yeasts that are quietly perpetuating the infection.

Our panel resolves 12 targets — including MRSA via mecA/C and three clinically relevant Candida species — from a single wound swab in 24–48 hours.

By the Numbers

The clinical weight behind this panel.

Industry statistics from public-health bodies and peer-reviewed literature — context for why this testing matters.

6.5M+
Americans living with chronic, non-healing wounds
Source · NIH / Wound Healing Society
$28B
annual U.S. Medicare spend on chronic wound care
Source · Nussbaum et al., Value in Health
Polymicrobial
majority of chronic wounds harbor ≥3 organisms — often missed by culture
Source · Wound Repair Regen
MRSA
present in up to 30% of infected diabetic foot ulcers
Source · IDSA DFI Guidelines

Figures reflect publicly reported epidemiology and clinical literature for context only. They are not performance claims for the Chaseville Labs assay. See individual citations from the U.S. Centers for Disease Control and Prevention, World Health Organization, National Institutes of Health, and peer-reviewed journals.

What This Panel Diagnoses

Conditions, syndromes & infections covered.

The clinical scenarios where this panel is the right call — built around the differential your providers are actually working through.

Chronic & High-Risk Wounds

3
Diabetic Foot Ulcers (DFU)

Polymicrobial almost by definition — MRSA, Pseudomonas, anaerobes, Enterococcus, and Candida all common.

Clinical Impact ·Resolves the true organism mix so empirical broad-spectrum coverage can be narrowed — preserves limb and reduces amputation risk.
Pressure Ulcers (Stage III/IV)

Deep tissue infections with gram +/−, fungal, and viral pathogens — culture under-reports the drivers.

Clinical Impact ·Per-target results support targeted therapy and infection-control documentation for skilled-nursing settings.
Chronic Non-Healing Wounds

Wounds open >4 weeks despite standard care — fastidious organisms and biofilm-forming species often the cause.

Clinical Impact ·Identifies why the wound isn't healing and changes the treatment plan instead of repeating failed regimens.

Acute Surgical & Skin Infections

3
Surgical Site Infections (SSI)

Post-operative wound infection — every day of delayed organism ID raises readmission and reoperation risk.

Clinical Impact ·Rapid pathogen + resistance ID enables stewardship-driven post-op care and reduces hospital length of stay.
Cellulitis & Abscess

Streptococcus pyogenes, Staphylococcus aureus (including MRSA), and gram-negative drivers.

Clinical Impact ·Direct MRSA detection via mecA/C — switches empirical cephalexin to vancomycin, linezolid, or doxycycline immediately.
Burn Wound Infection

Pseudomonas, Acinetobacter, MRSA, and yeast — the classic burn-unit organism profile.

Clinical Impact ·Rapid ID drives targeted antibiotic selection and infection-control isolation decisions.

Candida & Resistance Markers

2
Candida Wound Co-Infection

Candida albicans, C. glabrata, and C. tropicalis in chronic wounds and DFU.

Clinical Impact ·Explains wounds that fail every antibacterial regimen — directs species-appropriate antifungal therapy.
MRSA Confirmation (mecA/C marker)

Direct methicillin-resistance gene detection — no waiting for phenotypic susceptibility.

Clinical Impact ·Same-day decision between beta-lactam, vancomycin, or alternative agents.
Complete Target List

12 targets, resolved from a single specimen.

Each organism below is reported individually as Detected, Not Detected, or Inconclusive — grouped here by pathogen class for clinical scanability.

Gram-Positive

5 targets
Staphylococcus aureusmecA/C (MRSA marker)Streptococcus pyogenesStreptococcus agalactiae (GBS)Enterococcus faecalis

Gram-Negative

4 targets
Escherichia coliPseudomonas aeruginosaKlebsiella pneumoniaeAcinetobacter calcoaceticus-baumannii complex

Fungi

3 targets
Candida albicansCandida glabrataCandida tropicalis
Why Molecular

Culture was built for a different century.

Multiplex real-time PCR resolves what culture and rapid antigen miss — fastidious organisms, polymicrobial infections, viruses, and resistance markers — from a single specimen.

Conventional
The Old Way

Culture & rapid antigen

  • 3–5 days
    Patient empirically treated before any answer arrives
  • Misses fastidious & viral organisms
    No growth ≠ no infection
  • Single-organism bias
    Polymicrobial infections under-reported
  • No resistance data
    Susceptibilities arrive a day later, if at all
  • Specimen-quality dependent
    Pre-treated patients culture negative
Multiplex PCR
The CRL Way

Wound Care on Bio-Rad CFX384

  • 24–48 hours
    Most reports back the next clinical day
  • 12 targets, one run
    Bacterial, viral, fungal, and parasitic in a single multiplex
  • Detects what culture can't
    Fastidious organisms, viruses, and polymicrobial infections, all reported individually
  • Validated LDT
    CLIA-certified, internally controlled, per-target Detected / Not Detected reporting
Primary Specimen
Wound swab, Copan E-swab
Collection Container
ESwab or sterile container
Volume
Per collection protocol
Storage
2–8°C up to 72 hours
Transport
Pre-paid FedEx Priority Overnight
Stability
Validated per storage condition
Chain of Custody
Barcoded, temperature-logged in transit
Result Format

Per-target results, with clinical context.

Every analyte is reported individually as Detected, Not Detected, or Inconclusive. What a Detected result means clinically depends on which category the target falls into:

Gram-Positive
Staphylococcus aureusmecA/C (MRSA marker)Streptococcus pyogenesStreptococcus agalactiae (GBS)Enterococcus faecalis
If Detected

Staph and Strep species are the most common wound pathogens. mecA/C detection confirms MRSA and directs vancomycin, linezolid, or alternatives over beta-lactams.

Gram-Negative
Escherichia coliPseudomonas aeruginosaKlebsiella pneumoniaeAcinetobacter calcoaceticus-baumannii complex
If Detected

Pseudomonas, E. coli, Klebsiella, and Acinetobacter typically indicate chronic, healthcare-associated, or deep-tissue infection and warrant broader gram-negative coverage with consideration of resistance markers.

Fungi
Candida albicansCandida glabrataCandida tropicalis
If Detected

Candida detection — particularly non-albicans species — explains wounds that fail antibacterial therapy and directs species-appropriate antifungal selection.

Qualitative multiplex real-time PCR (Bio-Rad CFX384)
Turnaround: 24–48 hours